Tournament Dates: 19-Nov-21 - 20-Mar-22
Champions: Hyderabad FC
Runners-Up: Kerala Blasters FC
2021-22 ISL Rankings
| Team | Played | Won | Lost | Draw | GF | GA | Points | |
|---|---|---|---|---|---|---|---|---|
 | Jamshedpur FC | 20 | 13 | 3 | 4 | 42 | 21 | 43 |
 | Hyderabad FC | 20 | 11 | 4 | 5 | 43 | 23 | 38 |
 | ATK Mohun Bagan | 20 | 10 | 3 | 7 | 37 | 26 | 37 |
 | Kerala Blasters FC | 20 | 9 | 4 | 7 | 34 | 24 | 34 |
 | Mumbai City FC | 20 | 9 | 7 | 4 | 36 | 31 | 31 |
 | Bengaluru FC | 20 | 8 | 7 | 5 | 32 | 27 | 29 |
 | Odisha FC | 20 | 6 | 9 | 5 | 31 | 43 | 23 |
 | Chennaiyin FC | 20 | 5 | 10 | 5 | 17 | 35 | 20 |
 | FC Goa | 20 | 4 | 9 | 7 | 29 | 35 | 19 |
 | NorthEast United FC | 20 | 3 | 12 | 5 | 25 | 43 | 14 |
 | SC East Bengal | 20 | 1 | 11 | 8 | 18 | 36 | 11 |
*Top 4 teams qualify for the Semi-Finals